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Pierre Cochat Selected Research

Oxalates

2/2022Long-Term Transplantation Outcomes in Patients With Primary Hyperoxaluria Type 1 Included in the European Hyperoxaluria Consortium (OxalEurope) Registry.
1/2022Safety, pharmacodynamics, and exposure-response modeling results from a first-in-human phase 1 study of nedosiran (PHYOX1) in primary hyperoxaluria.
11/2021A stone in the bone.
1/2021Lumasiran, an RNAi Therapeutic for Primary Hyperoxaluria Type 1.
1/2021Phase 1/2 Study of Lumasiran for Treatment of Primary Hyperoxaluria Type 1: A Placebo-Controlled Randomized Clinical Trial.
1/2021Plasma oxalate and eGFR are correlated in primary hyperoxaluria patients with maintained kidney function-data from three placebo-controlled studies.
12/2020Transplantation for Primary Hyperoxaluria Type 1: Designing New Strategies in the Era of Promising Therapeutic Perspectives.
1/2019Skin microvascular dysfunction as an early cardiovascular marker in primary hyperoxaluria type I.
1/2018Association between glomerular filtration rate (measured by high-performance liquid chromatography with iohexol) and plasma oxalate.
1/2017A randomised Phase I/II trial to evaluate the efficacy and safety of orally administered Oxalobacter formigenes to treat primary hyperoxaluria.
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Pierre Cochat Research Topics

Disease

18Hyperoxaluria (Oxaluria)
02/2022 - 04/2004
17Chronic Kidney Failure (Chronic Renal Failure)
12/2020 - 04/2005
16Renal Insufficiency (Renal Failure)
02/2022 - 11/2003
16Primary hyperoxaluria type 1
02/2022 - 01/2005
16Primary Hyperoxaluria (Oxaluria, Primary)
01/2022 - 08/2006
13Chronic Renal Insufficiency
01/2021 - 10/2008
12Cystinosis
01/2021 - 10/2001
11Nephrocalcinosis
02/2022 - 04/2004
9Hypertension (High Blood Pressure)
01/2019 - 06/2005
7Proteinuria
03/2014 - 12/2005
6Infections
11/2019 - 10/2002
6Nephrotic Syndrome (Syndrome, Nephrotic)
12/2013 - 04/2005
5Neoplasms (Cancer)
10/2021 - 04/2004
5Urolithiasis
04/2021 - 08/2006
5Kidney Diseases (Kidney Disease)
01/2021 - 06/2007
4Kidney Calculi (Kidney Stone)
02/2022 - 11/2011
4Inborn Genetic Diseases (Disease, Hereditary)
01/2021 - 04/2004
4Systemic Lupus Erythematosus (Libman-Sacks Disease)
01/2017 - 07/2009
4Acidosis
08/2012 - 04/2004
3Disease Progression
01/2021 - 12/2009
3Wounds and Injuries (Trauma)
11/2019 - 12/2015
3Pain (Aches)
01/2018 - 01/2006
3Bone Fractures (Bone Fracture)
01/2018 - 12/2015
3IGA Glomerulonephritis (IGA Nephropathy)
06/2015 - 06/2007
2Hypophosphatemia
11/2017 - 01/2016
2Vitamin D Deficiency
12/2016 - 08/2012
2Hypoparathyroidism
01/2016 - 02/2014
2Glomerulonephritis
06/2015 - 11/2009
2Cystinuria
05/2015 - 03/2010
2Liver Diseases (Liver Disease)
01/2015 - 10/2008
2Diarrhea
10/2014 - 12/2009
2Chronic Kidney Disease-Mineral and Bone Disorder (Renal Rickets)
02/2014 - 08/2012
2Schimke immunoosseous dysplasia
10/2013 - 09/2012
2Bone Diseases (Bone Disease)
08/2012 - 07/2009
2Hyperparathyroidism
08/2012 - 08/2009
2Hereditary Nephritis (Alport Syndrome)
03/2012 - 11/2009
2Body Weight (Weight, Body)
03/2011 - 03/2009
2Pierson syndrome
09/2010 - 02/2007
2Acute Kidney Injury (Acute Renal Failure)
12/2009 - 09/2005
2Bartter Syndrome (Syndrome, Bartter)
05/2009 - 01/2008
2Premature Birth (Birth, Premature)
05/2009 - 03/2008
2Pruritus (Itching)
03/2009 - 10/2008
2Hypersensitivity (Allergy)
10/2008 - 09/2008
2Interstitial Nephritis (Tubulointerstitial Nephritis)
10/2008 - 11/2003
2Renal Tubular Acidosis (Distal Renal Tubular Acidosis)
01/2008 - 05/2006

Drug/Important Bio-Agent (IBA)

22OxalatesIBA
02/2022 - 01/2005
9Cystine (L-Cystine)IBA
01/2020 - 10/2001
8EnzymesIBA
02/2022 - 08/2006
7glyoxylic acid (glyoxylate)IBA
01/2022 - 01/2005
7Cysteamine (Mercaptamine)FDA Link
01/2021 - 01/2012
7SteroidsIBA
03/2011 - 04/2005
5Alanine-glyoxylate transaminase (alanine-glyoxylate aminotransferase)IBA
04/2021 - 08/2006
5Pharmaceutical PreparationsIBA
04/2021 - 10/2002
5Biological ProductsIBA
03/2019 - 08/2009
4Calcium OxalateIBA
01/2016 - 06/2010
4CreatinineIBA
03/2011 - 04/2004
3Phosphates (Orthophosphate)IBA
11/2017 - 08/2012
3MineralsIBA
11/2017 - 06/2010
3CalciumIBA
12/2016 - 04/2004
3Vitamin DFDA LinkGeneric
12/2016 - 04/2004
3Antineutrophil Cytoplasmic Antibodies (ANCA)IBA
06/2015 - 04/2005
3Biomarkers (Surrogate Marker)IBA
09/2014 - 06/2010
3Antihypertensive Agents (Antihypertensives)IBA
03/2014 - 09/2005
3SaltsIBA
03/2014 - 05/2008
3Angiotensin-Converting Enzyme Inhibitors (ACE Inhibitors)IBA
03/2014 - 06/2007
3Proteins (Proteins, Gene)FDA Link
09/2010 - 11/2003
3laminin beta2 (S-laminin)IBA
09/2010 - 11/2004
3Cyclosporine (Ciclosporin)FDA LinkGeneric
10/2008 - 04/2005
2lumasiranIBA
01/2021 - 01/2021
2calcium phosphateIBA
11/2019 - 08/2012
2ElastinIBA
01/2019 - 09/2012
2Fibroblast Growth Factor-23IBA
11/2017 - 04/2010
2Phosphorus (Red Phosphorus)IBA
12/2016 - 07/2014
2Protons (Proton)IBA
08/2015 - 09/2014
2Pyridoxine (Pyridoxin)FDA LinkGeneric
01/2015 - 07/2011
2AdenineFDA LinkGeneric
01/2015 - 03/2010
2TransferasesIBA
01/2015 - 03/2010
2Complement System Proteins (Complement)IBA
12/2014 - 09/2009
2Peptidyl-Dipeptidase A (Angiotensin Converting Enzyme)IBA
03/2012 - 03/2008
2Cyclophosphamide (Cytoxan)FDA LinkGeneric
01/2011 - 12/2005
2Human Growth Hormone (Saizen)FDA LinkGeneric
12/2009 - 07/2009
2Calcineurin InhibitorsIBA
12/2009 - 10/2008
2melamineIBA
12/2009 - 07/2009
2Immunoglobulins (Immunoglobulin)IBA
11/2009 - 10/2008
2Uric Acid (Urate)IBA
12/2008 - 11/2003
2InulinFDA Link
10/2008 - 09/2008
2UromodulinIBA
09/2008 - 11/2003
2dirhodium tetraacetate (DRTA)IBA
01/2008 - 05/2006
1nedosiranIBA
01/2022

Therapy/Procedure

22Kidney Transplantation
02/2022 - 04/2004
15Therapeutics
10/2021 - 04/2005
11Transplantation
02/2022 - 04/2004
7Liver Transplantation
04/2021 - 08/2006
4Renal Replacement Therapy (Therapies, Renal Replacement)
12/2018 - 02/2007
3Peritoneal Dialysis
12/2020 - 04/2005
3Conservative Treatment
01/2018 - 01/2006
3Organ Transplantation
10/2010 - 04/2004
2Nephrectomy
11/2019 - 05/2015
2Bone Marrow Transplantation (Transplantation, Bone Marrow)
06/2015 - 10/2013
2Hemodiafiltration
12/2014 - 02/2014